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Umbilical cord stem cell banking bandwagon swells
With over 26 million births being registered every year in India, the
number of Stem cell banking companies in India is on the rise.
Enterprises ranging from India's largest corporate player
like Reliance Life Sciences to local non-government organizations (NGOs) are
making early investments in setting up stemcell and umbilical cord blood banks
across the country. While Cryobanks International, LifeCell, and Reliance have
already established themselves in the cord blood and stem cell banking space,
regional players are seeing this as a futuristic business option. This year
alone has witnessed the setting up of two companies.
The Reliance Life Sciences offers stem cell banking services
under the "Reli Cord" brand and is known to have direct presence in
more than 30 locations. Cryobanks has established its facility in Gurgaon with
an investment of Rs 35 crore. The company operates in over 25 cities and hopes
to harvest about 6,000 units during 2008. "We plan to increase the number
of offices from 25 to 50 by March 2008 and the client base from 1,500 to 6,000
this year," said Dr C V Nerikar, CEO, Cryobanks International India.
"We plan to set up about four banks across India in the next three to four
years. One would be in Delhi, one in Calcutta, one in Mumbai or Pune and one in
South or whichever place suits," he added.
LifeCell, in collaboration with Cryo-Cell International, USA
facilitates the cryogenic preservation of stem cells at its unique facility in
Chennai. LifeCell has set up a 21,000 sq ft laboratory at the cost of Rs 14
crore in the outskirts of Chennai and has more than 30 centers. The company has
centers in Dubai and Sri Lanka and plans to open centers in other countries as
well. LifeCell has recently inaugurated its area office and collection centre in
Indore and by 2009, the company plans to have more than 50 centers to cater to
the growing Indian market for stem cell banking. The facility has a capacity to
store over 1 lakh samples and conforms to the standards of American Association
of Blood Banks and US FDA.
The other players operating in this space include Cord Life
Biotech, Cryo Stem Cell, and Karnataka Stem Cell.
Chennai-based Jeevan Blood Bank is also setting up Jeevan
Stem Cell Bank. The main source of stem cells will be umbilical cord blood. IQRA
Biotech Services, claimed to be the first human DNA banking company based in
Lucknow, UP, also proposes to setup an umbilical cord blood bank by 2008-09.
Stem Cell Banks in India
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Reliance Life Sciences, Mumbai
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LifeCell, Chennai
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Cryobanks International, Gurgaon
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Jeevan Stem Cell Bank, Chennai
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Karnataka Stem Cell, Bangalore
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Cryo Stemcell, Bangalore
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Cord Life Biotech, Pune
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Apollo Hospital, Hyderabad
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Advanced Cell Therapeutics, Mumbai
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IQRA Biotech Services, Lucknow
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Histostem Inc. USA has signed MoUs
with the governments of Maharashtra and Andhra Pradesh.
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The Potential
Based on Frost & Sullivan's findings, the global stem
cell banking market size for 2005 was estimated to be $1.02 billion and it is
projected that this number would triple to $3.2 billion in 2010, at a compounded
annual growth rate (CAGR) of 25.8 percent. Stem cell preservation is a huge
business opportunity in the international market and as per estimates the global
stem cell market is expected to become $10 billion opportunity over next few
years.
India, having a very high birth rate, presents a lucrative
opportunity for stem cell banking business. With more than 26 million births a
year, India is poised to be the largest source for umbilical cord blood in the
world. Leading cell banking companies are keenly eyeing India for the potential
it carries in this segment and are contemplating to enter the Indian market
preferably via joint ventures with local companies.
According to industry observers, India has all the essential
ingredients to emerge as a key repository of cord blood for companies across the
globe. Leveraging the well developed logistics infrastructure, leading companies
can create huge storage capacities for their global and Asia-Pacific operations
in India, they said.
Trends
Most of the cord-cell banking companies are increasingly
looking at fostering links with medical institutes, hospitals, research
institutions and biotechnology companies to aid in stem sell research. "We
are looking at collaborating with lot of hospitals for taking stem cell research
forward. In this direction, we have already signed up certain agreements with
few hospitals in some of the metros," said Dr Nerikar. Many of the
stem-cell banking companies have also been focusing on stem cell therapy
centers. TRICell is an affiliate of LifeCell and has a therapeutics facility to
provide clinical applications under stem cell therapy. It has been set in
association with Sri Ramachandra University, Chennai. Cyrobanks is also in the
process of establishing a therapy center by the end of this year.
At present, lack of awareness among the common people about
the huge potential to be gained from the storage of cord blood stem cells and
highly technical nature of the process is the key reason for a small customer
base in the country. However, the market has tremendous potential that could be
tapped by initiating an awareness campaign and a customized marketing plan say
players in the industry.
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Applications
Cord blood stem cell transplantation
has moved over the last few years from being an experimental procedure
to an accepted treatment for a number of hematological diseases and
genetic disorders. Researchers suggest that some cord blood cells,
present in extremely low frequency, may have the capacity to develop
into many different lineages including cartilage, fat cells, hepatic and
cardiac cells. Originally stored for the treatment of hematological
disorders, these stem cells have now been found to be more versatile,
even pluripotent, with potential for use in the treatment of a broader
range of disorders and diseases and may be particularly valuable in cell
therapy and regenerative medicine. |
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Potential Indian
Patient Population for Stem Cell-Based Therapies |
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Condition |
Number of Patients |
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Cardiovascular Diseases |
58 million |
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Autoimmune Diseases |
30 million |
|
Diabetes |
32 million |
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Osteoporosis |
10 million |
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Cancers |
8.2 million |
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Alzheimers disease |
5.5 million |
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Parkinson's Disease |
5.5 million |
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Burns (Severe) |
0.3 million |
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Spinal-cord Injuries |
0.25 million |
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Birth Defects |
0.15 million/year |
Source: Dr. Vasantha Muthuswamy, Senior Deputy
Director General, ICMR
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