Stem cell therapy has become a reality in India. The All
India In stitute of Medical Sciences (AIIMS) has successfully given stem cell
treatment by 'injection method' to its cardiac patients.
The institute conducted the study under the leadership of P
Venugopal, a renowned heart surgeon and AIIMS, director, from February 2003 to
January 2005, where 35 cardiac patients were given stem cell therapy and were
monitored at six, 12, and 18 month intervals. All the patients were brought in
at a stage when their hearts were beyond bypass surgery and transplant was the
only solution. During the course of the treatment, there were no mortalities and
in fact after six months, 56 percent of the dead tissue area injected with stem
cells showed improvement. After eighteen months, the improvement spread to about
64 percent of the necrotic tissue area. These stem cells, derived from the
patient or donors, act as repair agents within the body, multiplying
continuously to replenish other cells.
The procedure uses robotics to inject stem cells into the
artery leading to the diseased organ, after blocking passage through the vein to
prevent loss in transit, in patients. The regenerative cells are delivered to
the affected area initiating the process of repair and regrowth of healthy
cells. This reduces the disease burden in some while completely curing others.
Besides cardiac patients, the stem cell injection method can
also be successfully used in patients with diabetes, neurological disorders,
muscular dystrophy and cerebral palsy. With further refinement, even immune
disorders and cancer can be treated with this stem cell procedure. Commenting
about this achievement, the Union health and family welfare minister, Anbumani
Ramadoss said, "The feat had placed AIIMS right at the top of the world's
medicine map."
This achievement has brought new laurels to AIIMS, as this is
a global first in stem cell medicine. AIIMS has now been notified as India's
nodal center for conducting and coordinating stem cell research. The medical
team can file for a patent as this procedure is one of its kind even though stem
cell technology has been applied successfully in the UK, Korea and China,
particularly in regenerating diseased cells. In fact, this treatment procedure
is so new that there are no clear regulatory guidelines for carrying out stem
cell transplants on heart patients undergoing bypass surgery. This has led to
fears that soon this may lead to a number of private health centers claiming
stem cell treatment for a wide range of diseases.
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